N-Methyl-D-aspartic Acid(NMDA) CAS NO.6384-92-5

one of manufacturers of NMDA

high quality

good price

fast delivery

Wuxi Cima Science Co.,Ltd is a professional manufacturer of herbal extracts and nutritional chemicals integrated production, R&D and marketing in China. We mainly provide herbal products, nutritional products, APIs, OEM service and technical supports. Product range covers food additives and ingredients; nutritional products for animal and human; pharmaceuticals; cosmetics; APIs; Chemical Intermediates and Biological pesticide.

Cima Science possesses four manufacturing bases and two modern laboratories, covering a vast area of ten thousand square meters. These four production bases have the capability to complete all the unit operations of fermentation, synthesis, extraction, concentration, separation and spray. The capacity can meet customersâ?? requirements from kilograms to hundreds of tons. Every production step is driven under GMP and SOP. High quality assurance and new technology products is offered by a R&D team including twenty scientists equipped with complete analytical equipments of GC,HPLC,TLC,IC,IR,UV,NMR,AAS.Meanwhile,we offer customized processing and OEM terminal product services. Integrated solutions are provided in fields of biological pesticide, medication&health and cosmetic.

Based on our guide line Whatever done for customers health, nutrition and beauty, we are focus on providing the best quality natural products and services for our clients.

Description
N-Methyl-D-Aspartic acid (NMDA) is a synthetic agonist of the NMDA receptor that mimics the binding action of the endogenous ligand glutamate. The NMDA receptor is a voltage-gated ion channel closely involved in memory, in spatial learning and perturbing the normal behavior of this receptor system with NMDA exposure has facilitated elucidation of NMDA receptor-mediated activities.
NMDA is a glutamate-like excitatory substance and is a particularly potent excitant. NMDA binds to NMDA-receptor and interacts with it. This interaction causes a conformational change in the receptor or associated membrane molecules, which opened pores to allow extracellular sodium ions to flow down their electrochemical gradient and depolarise the cell. However, NMDA is proved to be a poor substrate for the uptake transporters, suggesting that the excitatory effect could not be an indirect consequence of glutamate uptake. Besides that, NMDA is found to increase intracellular calcium and release arachidonic acid, both of which generate oxygen radicals, subsequently inducing neuronal death.

N-Methyl-D-aspartic acid or N-Methyl-D-aspartate (NMDA) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Unlike glutamate, NMDA only binds to and regulates the NMDA receptor and has no effect on other glutamate receptors. NMDA receptors are particularly important when they become overactive during withdrawal from alcohol as this causes symptoms such as agitation and, sometimes, epileptiform seizures.

English name: N-Methyl-D-aspartic acid

CAS: 6384-92-5

English alias:(R) -2- (Methylamino) succinic acid; NMDA; (2R) -2- (methylammonio) butanedioate

Chemical names:N-methyl-D-aspartic acid;NMDA; 6384-92-5; N-Methyl-D-aspartate; N-Methylaspartate; N methyl D aspartate;

Molecular formula: C5H8NO4

MW: 146.1219

Specification:  ≥98%

Melting point: 187-192 ℃

Solubility: slightly soluble

Package:1kg/bag,25kg/drum

Brand name:Cimasci

Package:1kg/drum,25kg/drum

Wuxi Cima Science Co.,Ltd is a professional manufacturer of herbal extracts and nutritional chemicals integrated production, R&D and marketing in China. We mainly provide herbal products, nutritional products, APIs, OEM service and technical supports. Product range covers food additives and ingredients; nutritional products for animal and human; pharmaceuticals; cosmetics; APIs; Chemical Intermediates and Biological pesticide.

Cima Science possesses four manufacturing bases and two modern laboratories, covering a vast area of ten thousand square meters. These four production bases have the capability to complete all the unit operations of fermentation, synthesis, extraction, concentration, separation and spray. The capacity can meet customersâ?? requirements from kilograms to hundreds of tons. Every production step is driven under GMP and SOP. High quality assurance and new technology products is offered by a R&D team including twenty scientists equipped with complete analytical equipments of GC,HPLC,TLC,IC,IR,UV,NMR,AAS.Meanwhile,we offer customized processing and OEM terminal product services. Integrated solutions are provided in fields of biological pesticide, medication&health and cosmetic.

Based on our guide line Whatever done for customers health, nutrition and beauty, we are focus on providing the best quality natural products and services for our clients.

Similar products:

Alpha GPC/PQQ/ Palmitoylethanolamide(PEA)/Vinpocetine/Oleoylethanolamide

Magnesium L-threonate/Bacopa extract/Huperzine A/CDP-Choline

Mulberry leaf extract/Resveratrol/Nigella Sativa Seeds Extract

garlic extract/red yeast rice(0.4%-5%Monacolin K)